TGF-β1 Sensitizes TRPV1 through Cdk5 Signaling in Odontoblast-Like Cells

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TGF-β1 sensitizes TRPV1 through Cdk5 signaling in odontoblast-like cells

BACKGROUND Odontoblasts are specialized cells that form dentin and they are believed to be sensors for tooth pain. Transforming growth factor-β1 (TGF-β1), a pro-inflammatory cytokine expressed early in odontoblasts, plays an important role in the immune response during tooth inflammation and infection. TGF-β1 is also known to participate in pain signaling by regulating cyclin-dependent kinase 5...

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Toxicity of chlorhexidine on odontoblast-like cells

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ژورنال

عنوان ژورنال: Molecular Pain

سال: 2013

ISSN: 1744-8069,1744-8069

DOI: 10.1186/1744-8069-9-24